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临床试验/NCT07544342
NCT07544342已完成不适用

Assessment of Risk Factors for Acquiring Colonization With Candida Auris During an Outbreak in ICU.

Barzilai Medical Center1 个研究点 分布在 1 个国家目标入组 771 人开始时间: 2026年2月15日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
771
试验地点
1
主要终点
Colonization with Candida auris

研究概览

简要总结

The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.

详细描述

Candida auris is unique when compared to other pathogenic fungi, as it spreads in the hospital rapidly. Therefore, it can cause healthcare-associated infections and outbreaks, it is resistant to antimicrobials and disinfectants and it is persisting on human skin and in the inanimate environment. There are few works listing factors found associated with candida auris candidemia, including longer CVC days, prior antibiotics, mechanical ventilation and longer ICU stay. Most of the research for candida auris risk factor doesn't differentiate colonization and infection, or, focuses on risk factors leading from colonization to infection. The study is aimed to assess the risk factors for acquiring candida auris skin colonization during an outbreak in an ICU.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • hospitalization in ICU
  • Screened for candida auris

排除标准

  • Age <18 yeas.
  • No candida screen.

研究组 & 干预措施

Colonized

Patient colonized with candida auris

Non colonized

Patient not colonized with candida auris

结局指标

主要结局

Colonization with Candida auris

时间窗: From hospitalization in ICU until 2 weeks following discharge from ICU, a maximum of 90 days.

Positive screening for candida auris, taken by nose/ armpits and groin swabs and either directly seeded on a selective medium or by positive PCR.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Dr. Daniel Leshin Carmel

Head of infection control

Barzilai Medical Center

研究点 (1)

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