Evaluation of the Effects of Spinal Versus General Anesthesia on Transcranial Cerebral Oxygen Saturation in Geriatric Patients Undergoing Total Hip Arthroplasty
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 82
- 主要终点
- Change in transcranial regional cerebral oxygenation (rSO2)
研究概览
简要总结
The purpose of the study is to compare the effects of spinal and general anesthesia on transcranial regional cerebral oxygen saturation in geriatric patients undergoing total hip arthroplasty.
详细描述
Geriatric patients who received anesthesia undergoing total hip arthroplasty were randomized by means of a computer-generated randomization order into two groups; general anesthesia group (Group 1) and spinal anesthesia group (Group 2). Before and after induction of the general or spinal anesthesia, patients were monitorized with near infrared spectroscopy for regional cerebral oxygen saturation. Findings were compared statistically.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 90 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients who undergo elective total hip arthroplasty
- •American Society of Anesthesiologists class 1 to 3
- •Ability to consent
排除标准
- •Pulmonary disease
- •History of allergic reaction to local anaesthetics
- •Peripheral neuropathy
- •Neurologic disease
- •Coagulation disorders
研究组 & 干预措施
general anesthesia
Patients in this group were randomized to receive general anesthesia.
干预措施: general anesthesia (Other)
spinal anesthesia
Patients in this group were randomized to receive spinal anesthesia.
干预措施: spinal anesthesia (Other)
结局指标
主要结局
Change in transcranial regional cerebral oxygenation (rSO2)
时间窗: 60 minutes
Assessed every 5 minutes during the procedure
次要结局
- Post anesthetic complications(1 day)