Comparison of the Effect of General and Spinal Anesthesia on Umbilical Neutrophil-to-lymphocyte Ratio, Platelet-to-lymphocyte Ratio and Mean Platelet Volume in Patients Undergoing Cesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- neutrophil-to-lymphocyte ratio
研究概览
简要总结
The aim of the study was to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) in patients undergoing cesarean section.
详细描述
This study was designed to evaluate the effects of anesthetic techniques (general and spinal anesthesia) on umbilical cord NLR, PLR and MPV in patients undergoing cesarean section.
The primary endpoint was to compare the effects of general and spinal anesthesia on umbilical cord NLR. Secondary endpoints were determined the general and spinal anesthesia on routine umbilical cord PLR, MPV and newborn Apgar scores at 1st and 5th min.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 - 45 years
- •American Society of Anesthesiology (ASA) II-III
- •elective ceserean surgery
排除标准
- •declining to give written informed consent
- •under 18 years of age or over 45 years of age
- •factors affecting NLR, PLR and MPV such as preeclampsia, HELLP syndrome or premature rupture of membranes
- •history of neurological and/or neuromucular disease
- •cooperation cannot be established
- •emergency surgery
结局指标
主要结局
neutrophil-to-lymphocyte ratio
时间窗: within 5 minute, following delivery
Evaluate the effects of NLR in patients undergoing cesarean section
次要结局
- Newborn Apgar score 1st minute(1st minute after birth)
- platelet-to-lymphocyte ratio(within 5 minute, following delivery)
- Newborn Apgar score 5th minute(5th minute after birth)
- mean platelet volume(within 5 minute, following delivery)