Maternal Serum Homocysteine Levels and Uterine Artery Pulsatility Index as Predictors of Spontaneous Preterm Labor
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 主要终点
- The accuracy of serum homocysteine levels and uterine artery pulsatility indices (UtA-PI ) for prediction of preterm labor
研究概览
简要总结
Study included all pregnant women admitted with threatened preterm labor during the study period. All participants underwent estimation of maternal serum homocysteine level and assessment of uterine artery Doppler indices.
详细描述
Prospective cohort study. Study approval by local ethics committee. Informed written consent. Study included all pregnant women admitted with threatened preterm labor during the study period. All participants underwent estimation of maternal serum homocysteine level and assessment of uterine artery Doppler indices.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Singleton pregnancy
- •More than 28 and less than 35 gestational weeks.
- •Threatened preterm labor
排除标准
- •Medical disorders complicating pregnancy
- •Obstetric conditions complicating pregnancy (e.g., placenta previa, multiple gestation,PPROM, ....etc)
- •Fetal anomalies or distress
结局指标
主要结局
The accuracy of serum homocysteine levels and uterine artery pulsatility indices (UtA-PI ) for prediction of preterm labor
时间窗: Single measurement at the end of the study ( around 37 gestational weeks)
Sensitivity (%), specificity (%), positive predictive value (%), negative predictive value (%), positive likelihood ratio (number), negative likelihood ratio (number), accuracy (%) of serum homocysteine and UtA-PI for prediction of preterm labor
次要结局
- Gestational age at delivery(Single measurement at the end of the study ( around 37 gestational weeks))
- Demographic and clinical characteristics of the study groups(Single measurement on the day one of hospital admission between 28-35 gestational weeks)
研究者
Ahmed Walid Anwar Murad
Assisstant proffessor of Obestetrics &Gynecology
Benha University