The Analgesic Effect of Transcranial Direct Current Stimulation Over the Primary Motor Cortex on Central Neuropathic Pain Patients With Spinal Cord Injury
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Neuropathic Pain
- Sponsor
- Seoul National University Bundang Hospital
- Enrollment
- 16
- Locations
- 1
- Primary Endpoint
- Numeric rating scale for average pain over the preceding 24h
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
The purpose of this study is to evaluate the analgesic effect of transcranial direct current stimulation (tDCS) applied on motor cortex in patients with spinal cord injury who have chronic neuropathic pain.
Detailed Description
* anodal stimulation of the primary motor cortex (M1) * anode electrode: C3 (EEG 10/20 system) * cathode electrode: contralateral supraorbital area * constant current of 2mA intensity for 20 min * twice a day with a more than 4 hours interval during of 2 weeks (from Monday to Friday, total 20 treatment session)
Investigators
Hyung-Ik Shin
Associate Professor
Seoul National University Bundang Hospital
Eligibility Criteria
Inclusion Criteria
- •elapsed time since spinal cord injury more than 6 months
- •stable chronic pain for at least 3 preceding months
- •pain that was not attributable to cause other that neuropathic pain
- •pain that was resistant to various types of medications or physical or complementary medicine treatment
Exclusion Criteria
- •any kind of metal implant in the head
- •heart disease including having a cardiac maker
- •family or personal history of epilepsy, or neuropsychiatric illness
Outcomes
Primary Outcomes
Numeric rating scale for average pain over the preceding 24h
Time Frame: before the first tDCS session, and 1, 2, 4, 6 and 8 wk after the start of the stimulation
Secondary Outcomes
- Patient global impression of change for pain(before the first tDCS session, and 1, 2, 4, 6, and 8 wk after the start of the stimulation)