Identity fragmentation in patients with Dissociative Disorders, Post-Traumatic Stress Disorder, Borderline Personality Disorder, and Avoidant Personality Disorder

Recruiting

• Conditions: Ook bij psychische stoornissen: persoonlijkheids- en gedragsstoornissen, posttraumatische stressstoornis; personality disorder; severe dissociative disorders; trauma-related disorders; 10013465

• Registration Number: NL-OMON51541
• Lead Sponsor: Rijksuniversiteit Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 18 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 200

Inclusion Criteria

In order to be eligible to participate in this study, a patient must meet one
of the following criteria according to the DSM-5 criteria (APA, 2013):

• A main diagnosis of Dissociative Identity Disorder (300.14) or Other
specified Dissociative Disorder (300.15) as confirmed by using the
Multidimensional Inventory of Dissociation (MID; Dell, 2006) and the DID
section of the Dissociative Disorders Interview Schedule DSM-5 version (DDIS;
Ross et al., 1989)
• A main diagnosis of Avoidant Personality Disorder (301.82), as confirmed by
using the APD section of the SCID-5-PD interview (First et al., 2016)
• A main diagnosis of Borderline Personality Disorder (301.83), as confirmed by
using the BPD section of the SCID-5-P interview (First et al., 2016)
• A main diagnosis of Post-Traumatic Stress Disorder (309.81), as confirmed by
using the PTSD checklist for DSM-5 (PCL-5; Weathers et al., 2013) as a
consequence of childhood traumatic experiences before the age of 12

In order to be eligible to participate as a healthy comparison, a participant
must not be currently diagnosed with a mental health disorder according to the
DSM-5 criteria (APA, 2013), including the disorders named above, as assessed by
using the MID, SCID-5-PV and PCL-5.

Participants with DID who can switch between several identity states must:
• be able to switch on demand between a self-selected trauma-fixated
identity, a trauma-avoidant identity, and an overview identity state
• be able to perform the tasks in these identity states without
spontaneously switching to other identities
• be able to perform the tasks in these identity states without
interference of other identities

Participants with OSDD will not be asked to switch between identity states

Exclusion Criteria

A potential participant who meets any of the following criteria will be
excluded from participation in this study:
- Severe current substance abuse (e.g., the use of hallucinogens, cannabis,
amphetamine-type stimulants and cocaine; DSM-5)
- Lack of fluency in Dutch
- Below the age of 18 or above the age of 65
- An IQ below 80
- For ethical reasons, those patients who are currently in crisis (i.e.,
immediate danger to oneself or others) will be excluded (e.g., acute high risk
of suicide or severe self-injurious behavior, or severe aggression-control
problems)

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are the outcomes of the cognitive tasks. For the<br /><br>hyperassociativity task an emotional detour score and a hyperassociativity<br /><br>score; for the card-sorting task scores on self-complexity,<br /><br>compartmentalization, overlap, differential importance, and proportion of<br /><br>negative attributes; for the emotion perception task an emotion recognition<br /><br>accuracy score and an emotion sensitivity score; for the future<br /><br>autobiographical memory test a future event specificity score; and finally for<br /><br>the dichotomous thinking task, a dichotomous thinking score, splitting score,<br /><br>and negative thinking score.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Other study parameters pertain to relevant sample demographics and<br /><br>characteristics:<br /><br>- Diagnosis<br /><br>- Insomia<br /><br>- Emotion regulation<br /><br>- Interpersonal functioning<br /><br>- Childhood traumatic experiences<br /><br>- Dissocation-related metamemory beliefs<br /><br>- Vividness of visual and verbal imagination<br /><br>- Identity style<br /><br>- Alexithymia<br /><br>- Experiential avoidance<br /><br>- Dissociation between self-states</p><br>