Effect of addition of different drugs before layngoscopy and intubation to prevent rise in BP and heart rate in patients undergoing general anaesthesia
Not Applicable
Completed
- Conditions
- Health Condition 1: null- General Surgery
- Registration Number
- CTRI/2018/03/012744
- Lead Sponsor
- SGRDIMSR
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
ASA physical status I and II
Scheduled for elective surgery under GA
Exclusion Criteria
1. ASA III and above
2. Major hepatic, renal or cardiovascular dysfunction
3. Pregnancy, PIH
4. Patients on anticoagulation therapy
5. Postural hypotension
6. Anticipated difficult airway
7. Uncontrolled hypertension and myocardial disease
8. Surgeries involving anticipated major blood losses and fluid shifts
9. Patients on sedatives other than used for study
10. Patients with drug allergies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Attenuation haemodynamic stress response to laryngoscopy and intubationTimepoint: 15 minutes after study drug infusion till 30 minutes post-intubation
- Secondary Outcome Measures
Name Time Method Propofol and muscle relaxant sparing effect of dexmedetomidine and magnesium sulphate, respectivelyTimepoint: 15 minutes after study drug infusion till whole of intraoperative period