Thoracic Paravertebral Block for Postoperative Pain Management in PACU After VATS Surgeries: A Randomized Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- King Hussein Cancer Center
- Enrollment
- 81
- Locations
- 1
- Primary Endpoint
- Opioid requirement in the PACU
Study Overview
Brief Summary
This randomized controlled trial evaluated the efficacy of a thoracic paravertebral block (TPVB) in reducing opioid requirements and pain intensity in the PACU after video-assisted thoracoscopic surgery (VATS).
Detailed Description
This randomized controlled trial evaluated the efficacy of a thoracic paravertebral block (TPVB) in reducing opioid requirements and pain intensity in the PACU after video-assisted thoracoscopic surgery (VATS). Adult patients scheduled for elective VATS who meet the eligibility criteria will be randomized to either Arm:
Arm 1: General anesthesia with TPVB;
Arm 2: General anesthesia alone (control group).
Primary Outcome: to assess Opioid requirement in the PACU
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Adult patients scheduled for elective VATS, ASA physical status II-III, BMI 19-40.
Exclusion Criteria
- •Patient refusal, coagulation disorders, contraindications to TPVB, chronic analgesic use, mental illness
Arms & Interventions
General anesthesia with TPVB
0.4 ml/kg of 0.5% bupivacaine injected into the thoracic paravertebral space
Intervention: 0.4 ml/kg of 0.5% bupivacaine (Drug)
Outcomes
Primary Outcomes
Opioid requirement in the PACU
Time Frame: Opioid requirement assessed at 5 minutes, 15 minutes, 30 minutes post-PACU admission, and at PACU discharge (up to 4 hours)
Opioid requirement in the PACU, recorded as "yes" or "no."
Secondary Outcomes
- Pain intensity measured by Numeric Rating Scale -NRS(Pain intensity measured using the Numeric Rating Scale (NRS) at 5 minutes, 15 minutes, 30 minutes post-PACU admission, and at PACU discharge (up to 4 hours))