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Clinical Trials/NCT06689358
NCT06689358
Completed
N/A

Thoracic Paravertebral Block for Postoperative Pain Management in PACU After VATS Surgeries: A Randomized Controlled Trial

King Hussein Cancer Center1 site in 1 country81 target enrollmentNovember 1, 2022

Overview

Phase
N/A
Intervention
0.4 ml/kg of 0.5% bupivacaine
Conditions
Pain, Postoperative
Sponsor
King Hussein Cancer Center
Enrollment
81
Locations
1
Primary Endpoint
Opioid requirement in the PACU
Status
Completed
Last Updated
last year

Overview

Brief Summary

This randomized controlled trial evaluated the efficacy of a thoracic paravertebral block (TPVB) in reducing opioid requirements and pain intensity in the PACU after video-assisted thoracoscopic surgery (VATS).

Detailed Description

This randomized controlled trial evaluated the efficacy of a thoracic paravertebral block (TPVB) in reducing opioid requirements and pain intensity in the PACU after video-assisted thoracoscopic surgery (VATS). Adult patients scheduled for elective VATS who meet the eligibility criteria will be randomized to either Arm: Arm 1: General anesthesia with TPVB; Arm 2: General anesthesia alone (control group). Primary Outcome: to assess Opioid requirement in the PACU

Registry
clinicaltrials.gov
Start Date
November 1, 2022
End Date
August 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult patients scheduled for elective VATS, ASA physical status II-III, BMI 19-40.

Exclusion Criteria

  • Patient refusal, coagulation disorders, contraindications to TPVB, chronic analgesic use, mental illness

Arms & Interventions

General anesthesia with TPVB

0.4 ml/kg of 0.5% bupivacaine injected into the thoracic paravertebral space

Intervention: 0.4 ml/kg of 0.5% bupivacaine

Outcomes

Primary Outcomes

Opioid requirement in the PACU

Time Frame: Opioid requirement assessed at 5 minutes, 15 minutes, 30 minutes post-PACU admission, and at PACU discharge (up to 4 hours)

Opioid requirement in the PACU, recorded as "yes" or "no."

Secondary Outcomes

  • Pain intensity measured by Numeric Rating Scale -NRS(Pain intensity measured using the Numeric Rating Scale (NRS) at 5 minutes, 15 minutes, 30 minutes post-PACU admission, and at PACU discharge (up to 4 hours))

Study Sites (1)

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