Transversus Thoracic Plane Block for Perioperative Analgesia in Cardiac Surgery: a Randomized Controlled Prospective Study
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Transversus Thoracic Plane Block
- Sponsor
- Saint-Joseph University
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- postoperative pain score
- Status
- Not Yet Recruiting
- Last Updated
- last year
Overview
Brief Summary
The goal of this clinical trial is to learn if perioperative Transversus Thoracic Plane Block (TTPB) decrease perioperative pain after cardiac surgery. The main questions it aims to answer are:
- does Transversus Thoracic Plane Block decrease perioperative pain after cardiac surgery more than the standard analgesic treatment?
- Are the results different if the investigators perform Transversus Thoracic Plane Block before surgery or at the end of surgery?
Investigators
Joanna Tohme
Medical Doctor, Principal investigator
Saint-Joseph University
Eligibility Criteria
Inclusion Criteria
- •All patients scheduled for cardiac surgery via sternotomy under cardiopulmonary bypass
Exclusion Criteria
- •Previous cardiac surgery
- •Urgent surgery
- •Pregnant women
- •Allergy to local anesthetics
- •Opioid dependence
- •Low ejection fraction \< 30%
- •Presence or onset of cognitive or neurological disorders preventing pain assessment
- •Infection at injection sites
- •Coagulopathy
- •Patients on dual antiplatelet therapy
Outcomes
Primary Outcomes
postoperative pain score
Time Frame: First 24h postoperatively
The primary outcome is Postoperative Pain Score: Numeric rating scale (NRS) ratings will be assessed at T1 (= upon patient awakening), T2 (= 12 hours postoperatively), T3 (= 24 hours postoperatively) as well as during various painful moments (coughing, drain removal, mobilization). Numeric rating scale (NRS) is a unidimensional measure of pain intensity. It consists of the patient evaluating his pain out of a series of numbers ranging from 0 to 10, where the 2 respective endpoints are "0 = no pain" and "10 = worst possible pain."
Secondary Outcomes
- Incidence of postoperative pneumonia and pneumothorax in cardiac intensive care unit(First 24h postoperatively)
- Perioperative opioid requirement(First 24h postoperatively)
- Time to first opioid administration(First 24h postoperatively)
- Length of stay at cardiac intensive care unit and hospital stay(3 months postoperatively)
- Time to extubation(First 24h postoperatively)
- Patient satisfaction at 24 hours post surgery(First 24h postoperatively)