A Study to compare how patients come out of anesthesia after surgery and disability of thinking after coming out of anesthesia after mastoidectomy surgery between opioid and opioid free groups
Phase 2
- Conditions
- Health Condition 1: H60-H95- Diseases of the ear and mastoid process
- Registration Number
- CTRI/2024/05/067800
- Lead Sponsor
- Preethi S
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age between 18 to 65 years
ASA physical status 1 and 2
Exclusion Criteria
Taking opioid for chronic pain
Pregnant and nursing women
GCS less than 15 and heart rate less than 50 per min
Allergic to study medications
Psychiatric disorder and electrolyte imbalance
Hepatic and renal insufficiency
Unstable cardiorespiratory disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)Emergence time <br/ ><br>2)Extubation time <br/ ><br>3)recovery of cognitive functionsTimepoint: 1)Emergence time from administration of reversal agent to eye opening <br/ ><br>2)Extubation time from adminstration of reversal agent to tracheal extubation <br/ ><br>3)recovery of cognitive functions assessed using Short Orientation Memory Concentration test ater extubation at 5, 10 and 15mins
- Secondary Outcome Measures
Name Time Method 1) Intraoperative hemodynamic stability <br/ ><br>2)Postoperative pain assessmentTimepoint: 1)Intraoperatively patient monitored for hemodynamic stability by monitoring heart rate and blood pressure <br/ ><br>2)Postoperatively pain was assessed at 2, 6, 12 and 24hours using Numeric rating scale