Arterial dP/dt Dependency on Loading Conditions
Completed
- Conditions
- Intraoperative Hemodyamic Monitoring
- Registration Number
- NCT06164405
- Brief Summary
In the present study the investigators aim to assess the changes of the arterial dP/dtmax induced by fluids and vasoactive drugs during abdominal surgery
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 88
Inclusion Criteria
patients scheduled for abdominal surgery informed consent acceptance
Exclusion Criteria
- BMI> 30 Kg /m2;
- Atrial Fibrillation;
- Congestive heart failure with FE <35% and/or NYHA≥3;
- Severe known cardiac valve disease;
- Emergency surgery
- Shock or any acute conditions who required admission intensive care unit
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method dp/dt fluids dependency intraoperative measurement of dp/dtmax after fluid challenge
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie arterial dP/dtmax changes during fluid administration in abdominal surgery?
How does vasoactive drug-induced dP/dtmax modulation compare to standard hemodynamic monitoring techniques like MAP or SVV?
Which biomarkers correlate with fluid responsiveness and vasoactive drug efficacy in intraoperative arterial dP/dtmax assessments?
What adverse events are associated with fluid and vasopressor interventions during dP/dtmax-guided hemodynamic optimization?
How do combination therapies of fluids and vasopressors (e.g., norepinephrine, vasopressin) influence arterial dP/dtmax in surgical patients?
Trial Locations
- Locations (1)
Fondazione Policlinico Universitairo Agostino Gemelli
🇮🇹Roma, RM, Italy
Fondazione Policlinico Universitairo Agostino Gemelli🇮🇹Roma, RM, Italy