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临床试验/NCT02485782
NCT02485782已完成不适用

Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis

Medical University of Warsaw1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2015年6月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
48
试验地点
1
主要终点
Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on hemodialysis.

研究概览

简要总结

Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 - Haemodynamic Measurement System, Medis. GmbH Ilmenau) beginning 15 min prior to midweek dialysis session and continuous measurement thereafter, with a 15-min period after the termination of hemodialysis. Fluid overload were measured by BCM Monitor Fresenius before hemodialysis.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • give voluntary consent to participate in the study
  • patients on maintenance hemodialysis at least 3 months
  • stable dry weight
  • single-pool Kt/V >1.4
  • no clinical cardiovascular disease during the 6 months preceding entry

排除标准

  • not meet the above criteria
  • episode of illness (for example: infection)
  • pregnancy

结局指标

主要结局

Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on hemodialysis.

时间窗: 1 day

次要结局

  • Changes in volumetric hemodynamic parameter- systemic vascular resistance [dyn·s·cm-5] induced by fluid removal on hemodialysis.(1 day)
  • Changes in fluid removal parameter- thoracic fluid content [1/kOhm] during hemodialysis.(1 day)
  • Changes in blood pressure values [mmHg] induced by fluid removal on hemodialysis.(1 day)
  • Changes in volumetric hemodynamic parameter- stroke volume [ml] induced by fluid removal on hemodialysis.(1 day)

研究者

发起方
Medical University of Warsaw
申办方类型
Other
责任方
Principal Investigator
主要研究者

Łukasz Czyżewski

Łukasz Czyżewski

Medical University of Warsaw

研究点 (1)

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