Changes in Volumetric Hemodynamic Parameters Induced by Fluid Removal on Hemodialysis

Medical University of Warsaw1 site in 1 country48 target enrollmentJune 2015

ConditionsEnd Stage Renal Failure on Dialysis Body Fluid Retention Impedance Cardiac Output, Low

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: End Stage Renal Failure on Dialysis
Sponsor: Medical University of Warsaw
Enrollment: 48
Locations: 1
Primary Endpoint: Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on hemodialysis.
Status: Completed
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Changes in volumetric hemodynamic parameters and fluid overload (Cardiac Index,Stroke Volume, Thoracic Fluid Content, Systemic Vascular Resistance) were measured using a impedance cardiography (ICG) (CardioScreen 1000 - Haemodynamic Measurement System, Medis. GmbH Ilmenau) beginning 15 min prior to midweek dialysis session and continuous measurement thereafter, with a 15-min period after the termination of hemodialysis. Fluid overload were measured by BCM Monitor Fresenius before hemodialysis.

Registry

clinicaltrials.gov

Start Date

June 2015

End Date

September 2015

Last Updated

10 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Medical University of Warsaw

Responsible Party

Principal Investigator

Łukasz Czyżewski

Medical University of Warsaw

Eligibility Criteria

Inclusion Criteria

•give voluntary consent to participate in the study
•patients on maintenance hemodialysis at least 3 months
•stable dry weight
•single-pool Kt/V \>1.4
•no clinical cardiovascular disease during the 6 months preceding entry

Exclusion Criteria

•not meet the above criteria
•episode of illness (for example: infection)
•pregnancy

Outcomes

Primary Outcomes

Changes in volumetric hemodynamic parameter- cardiac index [l/min/m2]) induced by fluid removal on hemodialysis.

Time Frame: 1 day

Secondary Outcomes

Changes in volumetric hemodynamic parameter- systemic vascular resistance [dyn·s·cm-5] induced by fluid removal on hemodialysis.(1 day)
Changes in fluid removal parameter- thoracic fluid content [1/kOhm] during hemodialysis.(1 day)
Changes in blood pressure values [mmHg] induced by fluid removal on hemodialysis.(1 day)
Changes in volumetric hemodynamic parameter- stroke volume [ml] induced by fluid removal on hemodialysis.(1 day)