Comparison of Remifentanil and Lidocaine in attenuation of haemodynamic responses during intubation in patients undergoing general anesthesia
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- To compare the increase of heart rate between two groups
研究概览
简要总结
Comparision of Remifentanil and Lidocaine in reducing heart rate during intubation by recording heart rate at beseline 90 seconds after administration of study drugs 1minute and 3 minutes after intubation by dividing patients into two groups who belongs to ASA1 and 2 classification after randomization by computer generated numbers and study drugs are prepared by anesthetist who was not involved in anesthesia. the drug will be administered to both groups. the heartrate and blood pressure will be recorded after intubation at given time points i.e after 1 and 3 minutes of intubation. the data will be recorded and statistically analysed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1&2 Undergoing elective surgery under general anaesthesia.
排除标准
- •Known allergy to study drugs History of cardiovascular disease Patients on beta blockers or anti hypertensive medication Difficult airway or anticipated difficult intubation Emergency surgeries.
结局指标
主要结局
To compare the increase of heart rate between two groups
时间窗: T1 - Baseline | T2 - 90 seconds after administration of study drug | T3 - 1 minute after intubation | T4 - 3 minutes after intubation
次要结局
- Two record BP.(T1-BASE LINE)
研究者
DrChatrasapally Mohan Manikanta
ESIC medical college