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Clinical Trials/NCT05435690
NCT05435690
Active, Not Recruiting
N/A

Evaluation of a New Navigation System in Computer-assisted Total Knee Arthroplasty

GCS Ramsay Santé pour l'Enseignement et la Recherche1 site in 1 country126 target enrollmentJanuary 6, 2023
ConditionsGonarthrosis

Overview

Phase
N/A
Intervention
Not specified
Conditions
Gonarthrosis
Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Enrollment
126
Locations
1
Primary Endpoint
KSS M12
Status
Active, Not Recruiting
Last Updated
5 months ago

Overview

Brief Summary

Evaluation of a new navigation system in computer-assisted total knee arthroplasty.

Detailed Description

Single-blind, randomised, prospective comparative study in two parallel groups (conventional or computer-assisted arthroplasty). The patient will be evaluated during 3 visits: inclusion D0 (before arthroplasty), M3 (intermediate visit 3 months after arthroplasty) and M12 (final visit 12 months after arthroplasty).

Registry
clinicaltrials.gov
Start Date
January 6, 2023
End Date
May 31, 2026
Last Updated
5 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
GCS Ramsay Santé pour l'Enseignement et la Recherche
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult man or woman who has signed the informed consent for participation in the study,
  • Patient with primary uni or bilateral gonarthrosis
  • For whom an indication for total knee arthroplasty has been given

Exclusion Criteria

  • History of fracture, arthroplasty or osteotomy of the knee
  • Severe preoperative laxity warranting a constrained prosthesis
  • Inflammatory rheumatic disease or any other progressive concomitant condition that may impact on the patient's functional prognosis
  • Traumatic articular or extra-articular deformities of the lower limb
  • Neurological disease, after-effects of a stroke
  • Mental deficiency or any other reason that may hinder the understanding or the strict application of the protocol
  • Patient not affiliated to the French social security system
  • Patient under legal protection, guardianship or curatorship
  • Patient already included in another therapeutic study protocol or having participated in another trial in the previous three months

Outcomes

Primary Outcomes

KSS M12

Time Frame: Month 12

Assessment of functional outcome at 12 months by Knee Scoring System (KSS) score

Secondary Outcomes

  • KOOS JR M12(Month 12)
  • FJS M3(Month 3)
  • Hospitalization duration(Month 1)
  • KSS M3(Month 3)
  • EQ-5D M3(Month 3)
  • EQ-5D M12(Month 12)
  • FJS M312(Month 12)
  • Surgery duration(Day 0)
  • Postoperative outcome predictive factor(Month 1)
  • KOOS JR M3(Month 3)
  • Lower limb alignment(Month 12)
  • Safety analysis(Month 12)

Study Sites (1)

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