A Novel Method to Assess the Cornea Biomechanical Properties With Schiotz

Zhiwei Li1 site in 1 country1,000 target enrollmentFebruary 2015

ConditionsKeratoconus

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Keratoconus
Sponsor: Zhiwei Li
Enrollment: 1000
Locations: 1
Primary Endpoint: The Mulee factor obtained with Schiotz tonometer as a measure of cornea biomechanical property
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study aims to use Schiotz tonometer to evaluate the corneal biomechanical properties. The administration of Schiotz tonometer is according to the routine protocol which is use to measure intra-ocular pressure. The results obtained from Schiotz tonometer will be compared with results obtained from ORA and/or Corvis.

Detailed Description

Schiotz tonometer, since it firstly be developed more than 100 years ago by Hjalmar Schiotz, has been regarded as a classical method to evaluate intraocular pressure (IOP). In present study, we aims to measure the corneal biomechanical properties with schiotz tonometer and elucidate the clinical significance of this novel measurement. The corneal biomechanical property was calculated with subtracting the value displayed under loaded weight 5.5g from that under loaded weight 7.5g. We named the corneal biomechanical properties obtained with schiotz tonometer as Mulee factor, and the formulation is Mulee factor=value under loaded weight 7.5g (Value 7.5G)-value under loaded weight 5.5g (Value 5.5G).

Registry

clinicaltrials.gov

Start Date

February 2015

End Date

June 2016

Last Updated

10 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Zhiwei Li

Responsible Party

Sponsor Investigator

Principal Investigator

Zhiwei Li

Dr.

Shandong Provincial Hospital

Eligibility Criteria

Inclusion Criteria

•People without the disease mentioned in exclusion criteria part.

Exclusion Criteria

•Patients with ocular diseases including keratitis, conjunctivitis, history of chronic eye/systemic diseases except myopia and keratoconus, history of ocular surgery except LASIK, pregnant or lactating females.