Effecten van een hoge eiwitinname bij kinderen met obesitas.
- Conditions
- obesity, metabolic syndrome, insulin sensitivity
- Registration Number
- NL-OMON24325
- Lead Sponsor
- Sophia Children's Hospital - Erasmus MC Rotterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Boys & girls;
2. Obesity (BMI-SDS>2.3);
Exclusion Criteria
1. Obesity that is caused by a somatic treatable disorder;
2. Use of systemic steroids.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change in body composition (body fat%, fat-free mass, fat mass, fat-free mass index, fat mass index , waist and hip circumference, waist:hip ratio) in obese children who consumed a high protein diet for 4 weeks. Measurements will be performed with a DEXA-scan and the deuterium dilution technique.
- Secondary Outcome Measures
Name Time Method Whole body protein turnover, gluconeogenesis, energy expenditure, insulin sensitivity, and markers of dyslipidemia and oxidative stress, measured with stable isotoop techniques.