EUCTR2013-002883-20-NL进行中（未招募）不适用
Walking the Isobole of drug Interaction:Comparison of hemodynamic effects, cerebral and tissue oxygenation for 4 equipotent combinations of propofol and remifentanil
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-General anesthesia required for the procedure
- •-Age: 18 years and older
- •-American Society of Anesthesiologists (ASA) physical status I to III
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 80
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 20
排除标准
- •-Refusal to participate in this study
- •-Contra-indications for the use of propofol or remifentanil
- •-BMI > 35 kg/m2
- •-Central nervous system disorders (i.e. cerebrovascular accident, dementia, seizures, psychiatric disorders)
- •-Relevant hepatic disease (Child B or higher)
- •-Regular use of medication that affects the central nervous system (i.e. benzodiazepines, antidepressants, antipsychotics, antiepileptic drugs)
- •-Use of alpha-agonists or beta-blockers
- •-Overt signs of alcohol abuse
- •-Use of preoperative benzodiazepines (on the day of the study)
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