During 0peration thoracic nerve block given with 0.25% Levo-bupivacaine vs 0.25% Levo-bupivacaine plus dexmedetomidine for post-operative pain relief after breast cancer surgery – Randomized, Comparative and Controlled Study
Not Applicable
Completed
- Conditions
- Health Condition 1: C50- Malignant neoplasm of breast
- Registration Number
- CTRI/2020/12/030004
- Lead Sponsor
- IGIMS Patna
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 59
Inclusion Criteria
posted for modified radical mastectomy
Exclusion Criteria
1.Patient refusal
2.Local anaesthetic allergy
3.Bleeding diathesis
4.Locally advanced breast malignancy with infiltration of chest wall
5.Deranged liver function
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method – Duration of post-operative analgesiaTimepoint: – Duration of post-operative analgesia using NRS scale just after shifting the patient in PACU, then at the interval of 2 hour, 4 hour, 8 hour, 12 hour and 24 hour
- Secondary Outcome Measures
Name Time Method any side effects and total consumption of opioids in both groups.Timepoint: 24 hours
Related Research Topics
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What molecular mechanisms explain the analgesic synergy of levo-bupivacaine and dexmedetomidine in thoracic interfascial plane blocks for breast cancer surgery?
How does the efficacy of levo-bupivacaine plus dexmedetomidine compare to standard multimodal analgesia in post-MRM breast cancer patients?
Which biomarkers predict response to thoracic interfascial plane blocks using levo-bupivacaine with or without dexmedetomidine in C50 breast cancer patients?
What are the potential adverse events associated with intra-operative thoracic interfascial plane blocks using levo-bupivacaine and dexmedetomidine in breast cancer surgery?
What alternative adjuvants to dexmedetomidine are being evaluated in combination with levo-bupivacaine for post-operative analgesia in breast cancer patients?