Correction of vitamin D deficiency in chronic hepatitis C patients and effect on cytokines responses related to liver fibrotic pathway: A Randomized Double-Blind Placebo Control Study

Phase 4

Completed

• Conditions: Chronic hepatitis C patient; liver fibrosis, chronic hepatitis C, vitamin D suppelment

• Registration Number: TCTR20161103003
• Lead Sponsor: The Ratchadapiseksompotch Fund, Faculty of Medicine, Chulalongkorn University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2016-01-02
• Study Start: 2016-11-03
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 58

Inclusion Criteria

1.Chronic hepatitis c or CHC cirrhosis child A
2. 25-OH vitamin D < 30 ng/ml

Exclusion Criteria

1. HIV, DM, chronic lung disease
2. other cause of chronic hepatitis
3. preganancy
4. active bacterial infection
5. immunosuppresive drug
6. GFR < 60

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
matrixmetalloprotinase - 9 6 weeks after end of intervention Blood serum change

Secondary Outcome Measures

Name	Time	Method
PDGF, TIMP1, IL22 and IFN-γ 6 weeks after end of intervention Blood serum change