mHealth-Facilitated Physical Activity Toward Health (mPATH) Intervention for Low-Income Older Adults
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 176
- 试验地点
- 2
- 主要终点
- Change in episodic memory as assessed by the Cogstate Alzheimer's Battery
研究概览
简要总结
Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in low-income older adults. The study aims to test the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in low-income older adults.
详细描述
Low-income older adults (LIOA) are a population at higher risk to develop Alzheimer's disease and related dementias (ADRD) and sleep disturbances. Although empirical research suggests that physical activity interventions benefit cognition and sleep in older adults in general, the possible benefit of physical activity is understudied in LIOA. The growing wearable device and mobile Health (mHealth) provide an innovative approach to deliver individually tailored physical activity interventions at home with flexible schedules to overcome barriers to physical activity in LIOA. In addition, limited research has examined if physical activity interventions impact the individual's Amyloid/Tau/ Neurodegeneration (ATN) Alzheimer's disease biological state and whether physical activity may promote cognition through impacting sleep and AD pathology. This randomized controlled trial is designed to examine the immediate and sustaining efficacy of an mHealth-facilitated Physical Activity Toward Health (mPATH) intervention on cognitive function and sleep in LIOA. mPATH is a personalized physical activity intervention that includes personalized physical activity plans and training sessions, exercise at home by following personalized exercise videos, and biweekly phone coaching over 24 weeks, supported by wearable devices-enabled mHealth strategies. mHealth strategies and exercise videos will be used to support participant's physical activity during 6-12months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —(Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •self-reported difficulty of sleep
- •lack of physical activity/exercise
- •low household income
- •capacity for moderate intensity exercise
排除标准
- •untreated sleep apnea
- •severe depression or anxiety
- •history of neurologic or psychiatric disorders, neurodevelopmental impairment, traumatic brain injury
- •current enrollment in another clinical trial
研究组 & 干预措施
mPATH
mPATH is a personalized physical activity intervention that includes personalized physical activity plans and training sessions, exercise at home by following personalized exercise videos, and biweekly phone coaching over 24 weeks, supported by wearable devices-enabled mHealth strategies. mHealth strategies and exercise videos will be used to support participant's physical activity during 6-12months
干预措施: mPATH (Behavioral)
Education and Social control
This attention control group is designed to match the intervention for mPATH's staff-subject interaction duration through monthly home visits in the first 6 months
干预措施: Attention Control (Other)
结局指标
主要结局
Change in episodic memory as assessed by the Cogstate Alzheimer's Battery
时间窗: Baseline, 6 months, 12 months
Episodic memory will be measured by computerized cognitive batteries using the Cogstate Alzheimer's Battery.
Change in episodic memory as assessed by the Cogstate
时间窗: Baseline, 6 months, 12 months
Episodic memory will be measured by computerized cognitive batteries using Cogstate
次要结局
- Change in Sleep efficiency as assessed by actigraphy(Baseline, 6 months, 12 months)
