Physical Trainig and Cognitive Activity on the MCI Patient
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 5
- 试验地点
- 2
- 主要终点
- effectiveness of physical training
研究概览
简要总结
Regular physical activity is now recognized as a key element of good physical and mental health and this all ages.
MAIN GOAL : Evaluate the effectiveness of physical training associated with a cognitive training in improving the cognitive function of patients diagnosed with Mild Cognitive Impairment (MCI).
DESIGN : Controlled randomized monocentric and prospective study with clinical benefit for the patient with three groups : one physical training and cognitive exercise group, one physical training without cognitive exercise group and one control group.
In agreement with the literature on the effects of physiological stress on cognitive performance, the investigators expect the best cognitive test scores in groups with exercise training compared with controls (35% versus 80% error), and better scores on the MMSE, IALD, depression Scale, Index of Pittsburg sleep quality and quality of Life Questionnaire. Furthermore the investigators hypothesize that this positive effect is greater in the physical training and cognitive exercise group compared with the physical training group only.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed patient MCI (Mild Cognitive Impairment)
- •Elderly from 40 to 75 years old
- •MMSE upper to 22
- •Affiliated or beneficiary of a national insurance scheme
- •Medical capacity to the physical proposed activity (filling of the conditions of the Medical certificate of not contraindication in the sport)
排除标准
- •The placed persons under guardianship, under protection of justice,
- •The private persons of freedom (administrative or judicial)
- •Nobody already participating in a clinical trial
结局指标
主要结局
effectiveness of physical training
时间窗: up to 3 months
Assess the effectiveness of physical training associated with a cognitive training in improving the cognitive functions of patients diagnosed with Mild Cognitive Impairment (MCI). We expect the best cognitive test scores in groups with exercise training compared with controls (35% versus 80% error), and better scores on the MMSE, IALD, depression Scale, Index of Pittsburg sleep quality and quality of Life Questionnaire.
次要结局
- Cognitive improvement(up to 3 months)