The Effects of Physical Activity and Cognitive Training in Improving Cognitive Function of Institutionalized Older Residents
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Cognitive Decline
- Sponsor
- National Taiwan University Hospital
- Enrollment
- 270
- Locations
- 1
- Primary Endpoint
- Change from Baseline Cognitive Function at 8 weeks and 16weeks
- Last Updated
- 12 years ago
Overview
Brief Summary
Investigators assume that there are some positive effects of cognitive training and physical activities on cognitive function, depression and quality of life in a sample of older residents in long-term care facilities.
The purpose of this study is to explore the effects of various interventions (physical activity, cognitive training, integration of physical activity and cognitive training) on different outcome indictors in institutionalized older residents.
Detailed Description
1. to develop an intervention protocol that achieves clinical development objectives in a scientifically rigorous and time efficient manner. 2. to further analyze the effects of the various interventions and make a comparison of dose-response relation and efficacy.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age 65 year and older
- •Able to communicate verbally
- •Able to discern 5\*5 cm2 picture from a viewing distance of 20 cm
- •Able to hear a sound of normal speech from a distance of 20 cm
- •Able to sit in a chair or wheelchair independently for more than 30 minutes without changes in vital signs and awareness and without physical discomfort
- •Has cognitive decline status assessing by CASI 2.0
- •Lived in long-term care facilities during the study
Exclusion Criteria
- •Complete aphasia, blindness, deafness or completely dependent
- •Unstable angina, arrythmia, myocardial infarction history, postural hypotension, transient cerebral hypoxia or other psychiatric disorders except depression
- •Thrombophlebitis, or malignancy of the limbs.
- •Refusal by patient or family member.
- •Others. Reason to be well documented.
Outcomes
Primary Outcomes
Change from Baseline Cognitive Function at 8 weeks and 16weeks
Time Frame: pre-treatment (0 week, T0), post-treatment (8 weeks, T1) and follow-up (16 weeks, T2 )
Cognitive Function: Cognitive Assessment Screening Instrument (CASI) 2.0 in Chinese version
Secondary Outcomes
- Change from Baseline Depression at 8 weeks and 16weeks(pre-treatment (0 week, T0), post-treatment (8 weeks, T1) and follow-up (16 weeks, T2 ))
- Change from Baseline Quality of Life at 8 weeks and 16weeksStatus:(pre-treatment (0 week, T0), post-treatment (8 weeks, T1) and follow-up (16 weeks, T2 ))