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Efficacy and Safety of Lumiracoxib 400 mg in Arthroscopic Knee Surgery

Phase 4
Completed
Conditions
Pain
Registration Number
NCT00333567
Lead Sponsor
Novartis
Brief Summary

This study is designed to investigate the efficacy and safety of a single daily dose of 400 mg lumiracoxib given pre-emptively versus post-operatively in terms of efficacy in reducing pain associated with ambulatory arthroscopic knee surgery

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
110
Inclusion Criteria
  • Patients who need scheduled minor ambulatory arthroscopic knee surgery.
Exclusion Criteria
  • Patients with any surgical or medical conditions which could place the patient at higher risk from his/her participation in the study, or are likely to prevent the patient from complying with the requirements of the study or completing the trial period.

Other protocol-defined inclusion/exclusion criteria may apply.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Pain Intensity (PI) in the target knee after movement at the 2 h time-point
Secondary Outcome Measures
NameTimeMethod
PI at 1, 2, 3, 4 and 24 h time-points while at rest
PI at 1, 3, 4 and 24 h time-points after movement
Time to first rescue medication intake
Patient's global evaluation of response to study medication
Safety and tolerability profile

Trial Locations

Locations (1)

Novartis

🇩🇪

Nuernberg, Germany

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