Randomized Controlled Trial of Milk Products and Physical Activity on Body Composition and Health in Overweight Young Males

Not Applicable

• Conditions: Overweight
• Interventions: Other: Increased Dairy Intake; Other: Supplemental carbohydrate

• Registration Number: NCT01553370
• Lead Sponsor: Brock University

Brief Summary

Maintaining a healthy body weight is a major challenge for the majority of Canadians. A lifestyle strategy that promotes maintenance of a healthy body weight and, perhaps most importantly, can be incorporated into daily life with relative ease is essential. This study will determine if an effective strategy includes increased physical activity in conjunction with higher intakes of dairy products immediately following exercise. Fifty-six overweight adult males who do not regularly exercise will be assigned to one of four groups for 12 weeks. All groups will preform 12 weeks of exercise training (1 hour of cycling per day, 5 times per week). Two groups will consume supplemental low fat milk (3 servings per day) with one these groups consuming it immediately after exercise while the other will consume it either well before or long after the exercise session. The other two groups will consume a carbohydrate drink that has the same amount of energy as the low fat milk, with one of these groups consuming the drink right after exercise and the other another group will consume it either well before or long after the exercise session. Markers of health status including body weight, muscle mass, and bone mass will be measured at the start and after the 12- week intervention. The investigators anticipate that providing the low fat milk immediately after exercise will result in the most favorable changes in health outcomes, and provide a realistic lifestyle intervention for overweight individuals to attain a healthy body weight, and by doing so, optimize their ability to prevent chronic disease.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-03
• Study First Submitted: 2012-03-12
• Study First Submitted QC: 2012-03-13
• Last Update Submitted: 2012-03-13
• Study First Posted: 2012-03-14
• Last Update Posted: 2012-03-14
• Study Start: 2012-04
• Primary Completion: 2012-12
• Study Completion: 2013-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Male
• Target Recruitment: 54

Inclusion Criteria

• BMI greater or equal to 25
• healthy

Exclusion Criteria

• any chronic cardiovascular condition or metabolic condition
• kidney disease
• gastro-intestinal disease
• milk or dairy protein allergies
• lactose intolerance
• chronic lung conditions
• any condition that could potentially prevent participant from performing exercise
• allergy to local anaesthetics
• cumulative x-ray exposure and cumulative muscle biopsies

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Alternate Intake-time	Increased Dairy Intake	-
Alternate Intake-time	Supplemental carbohydrate	-
Immediately post-exercise	Increased Dairy Intake	-
Immediately post-exercise	Supplemental carbohydrate	-

Primary Outcome Measures

Name	Time	Method
Body composition	12 weeks
Bone mineral density	12 weeks
VO2 peak	12 weeks

Secondary Outcome Measures

Name	Time	Method
mitochondrial enzyme activity	12 weeks
muscle oxidative stress	12 weeks
muscle capillary density	12 weeks
blood lipids	12 weeks
blood inflammatory markers	12 weeks
blood markers of bone turnover	12 weeks

Trial Locations

Locations (1)

Brock University; 🇨🇦 St. Catharines, Ontario, Canada