Inspiratory Muscle Training in Patients Receiving Allogenic Stem Cell Transplantation

Not Applicable

• Conditions: Inspiratory Muscle Training; Stem Cell Transplantation; Respiratory Muscle Training
• Interventions: Other: inspiratory muscle training

• Registration Number: NCT01281410
• Lead Sponsor: Elisabethinen Hospital

Brief Summary

The study is a monocentric, controlled randomized trial. Its an interventional method study. There is a control and an interventional group. The interventional group is receiving a specific inspiratory muscle training with "Respifit" (special device for inspiratory muscle training) during the first 30 days after allogenic stem cell transplantation.

The investigators want to show that the training group gets stronger inspiratory muscles. The investigators measure the change of PIMAX values and MVV values.

Detailed Description

Not available

Study Timeline

• Status Verified: 2010-11
• Study Start: 2011-01
• Study First Submitted: 2011-01-18
• Study First Submitted QC: 2011-01-21
• Study First Posted: 2011-01-24
• Last Update Submitted: 2011-06-30
• Last Update Posted: 2011-07-04
• Primary Completion: 2013-02
• Study Completion: 2013-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 106

Inclusion Criteria

• Patients receiving allogenic stem cell transplantation
• Age 17 - 80 years old
• Informed consent

Exclusion Criteria

• Actual pneumonia at the beginning of the trial
• Impaired vision
• Patient is not able to handle "Respifit"

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Inspiratory muscle training	inspiratory muscle training	Inspiratory muscle training with a device named Respifit in addition to the usual physiotherapy program

Primary Outcome Measures

Name	Time	Method
Change of PI max-value from baseline at 30 days after stem cell transplantation	baseline and 30 days after stem cell transplantation	max strength of the inspiratory muscles
Change of MVV-value from baseline at 30 days after transplantation	baseline and 30 days after stem cell transplantation	max voluntary volume for Inspiratory muscle endurance

Secondary Outcome Measures

Name	Time	Method
inpatient days	from baseline to maximal 60 days after stem cell transplantation
Incidence of pneumonia	from baseline to 30 days after stem cell transplantation

Trial Locations

Locations (1)

Elisabethinen Hospital; 🇦🇹 Linz, Austria