A Clinical trial to study the effect of fentanyl and buprenorphine in spinal anesthesia to decrease the post-operative pain in patients undergoing lower abdominal surgeries.
Phase 4
- Conditions
- Health Condition 1: K421- Umbilical hernia with gangrene
- Registration Number
- CTRI/2024/01/061835
- Lead Sponsor
- Mahatma Gandhi Institute Of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anesthesiologist Grade I and II patients.
Age 18-65 years of either gender.
Patients undergoing infraumbilical Surgeries.
Height is more than 4 feet.
Patients willing to give consent.
Exclusion Criteria
American Society of Anesthesiologists Grade III and IV patients.
Patients with known contraindications for spinal anesthesia: bleeding disorders, local infection.
Patients with cardiovascular instability.
Patients with comorbidities like Hypertension, Diabetes Mellitus, cardiac diseases, etc.
Patient with allergy to opioids or history of hypersensitivity to local anesthetics.
Emergency surgeries.
Patients with a history of severe PDPH or PONV after spinal anesthesia.
Patients not willing to give informed written consent.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the duration of sensory & motor blockade.Timepoint: 15min 30min 45min
- Secondary Outcome Measures
Name Time Method 1. The onset of sensory & motor blocks was achieved. <br/ ><br>2.The level of blockade achieved. <br/ ><br>3. The efficacy of postoperative analgesia. <br/ ><br>4. Side effects like hemodynamic changes (hypotension and bradycardia) sedation, pruritus, post-operative nausea and vomiting and respiratory depression. <br/ ><br>Timepoint: 15min, 30min,45min