Early treatment of patients with undifferentiated arthritis (UA) with Methotrexate (MTX)
- Conditions
- ndifferentiated arthritis, probable rheumatoid arthritis according to ACR-1958 criteriaMusculoskeletal DiseasesOther arthrosis
- Registration Number
- ISRCTN21334657
- Lead Sponsor
- eiden University Medical Center (LUMC) (Netherlands)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 110
1. Diagnosis probable RA according to the ACR-1958 criteria
2. Aged 18 years or older
3. Less than 2 years of complaints
4. No DMARD use in the past (except Prednisone, maximal 3 months)
5. Signed informed consent
1. Diagnosis RA according to the ACR-1987 criteria
2. Kidney disorder: creatinine >150umol/l or estimated clearance < 75
3. Liver function disorder: ASAT, ALAT > 3x normal values
4. Alcoholism
5. Bone marrow insufficiency
6. Pregnant or pregnancy wish during study or 3 months thereafter
7. No adequate method of birth control
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
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