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临床试验/ISRCTN21334657
ISRCTN21334657已完成不适用

Early treatment of patients with undifferentiated arthritis (UA) with Methotrexate (MTX)

eiden University Medical Center (LUMC) (Netherlands)0 个研究点目标入组 110 人开始时间: 2005年9月12日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
110

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

性别
All

入选标准

  • 1. Diagnosis probable RA according to the ACR-1958 criteria
  • 2. Aged 18 years or older
  • 3. Less than 2 years of complaints
  • 4. No DMARD use in the past (except Prednisone, maximal 3 months)
  • 5. Signed informed consent

排除标准

  • 1. Diagnosis RA according to the ACR-1987 criteria
  • 2. Kidney disorder: creatinine >150umol/l or estimated clearance < 75
  • 3. Liver function disorder: ASAT, ALAT > 3x normal values
  • 4. Alcoholism
  • 5. Bone marrow insufficiency
  • 6. Pregnant or pregnancy wish during study or 3 months thereafter
  • 7. No adequate method of birth control

研究者

发起方
eiden University Medical Center (LUMC) (Netherlands)

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