ISRCTN13825020已完成未知
Effects of prenylflavonoids of beer and dealcoholised beer on bone mineral density and molecular bone markers
CIBER (Consorcio Centro de Investigación Biomédica en Red, M.P.)0 个研究点目标入组 37 人开始时间: 2018年1月2日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 37
研究概览
简要总结
2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36458171/ (added 06/04/2023) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37402233/ Effect on cardiovascular health (added 05/07/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •Current participant inclusion criteria as of 20/05/2022:
- •1. Postmenopausal women between 45 and 70 years of age
- •2. FSH 23-116 U/l
- •3. Estradiol (E2) <37 pg/ml
- •4. Amenorrhea =12 months
- •Previous participant inclusion criteria:
- •1. Women between 45 and 70 years of age within 5 years of menopause
- •2. FSH > 3 Miu/mL
- •3. Estradiol (E2) = 30 pg/mL
- •4. Amenorrhea = 12 months
排除标准
- •Current participant exclusion criteria as of 08/08/2022:
- •1. Patients with known diseases affecting bone metabolism (rheumatoid arthritis, hyperthyroidism, hypercortisolism, renal bone disease, chronic liver disease, among others)
- •2. Use of drugs affecting bone metabolism (fluorides, bisphosphonates, calcitonin, teriparatide or parathormone, strontium ranelate, SERMs, estrogen therapy, anabolic steroids, chronic glucocorticoids (>3 months), cytostatics, antiandrogens, and antiepileptics)
- •3. Participants who received silicon or polyphenol supplements
- •Previous participant exclusion criteria as of 20/05/2022:
- •1. Patients with known diseases affecting bone metabolism (rheumatoid arthritis, hyperthyroidism, hypercortisolism, renal bone disease, chronic liver disease, among others)
- •2. Participants who received silicon or polyphenol supplements
- •Previous participant exclusion criteria:
- •1. Patients with known diseases affecting bone metabolism (rheumatoid arthritis, hyperthyroidism, surgical menopause, hypercortisolism, renal bone disease, chronic liver disease, among others)
- •2. Use of drugs affecting bone metabolism (fluorides, bisphosphonates, calcitonin, teriparatide or parathormone, strontium ranelate, SERMs, estrogen therapy, anabolic steroids, chronic glucocorticoids (> 3 months), cytostatics, antiandrogens and antiepileptics)
- •3. Participants who received silicon or polyphenol supplements
研究者
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