Effect of food on oral flucloxacillin pharmacokinetics and pharmacodynamics in healthy volunteers
Phase 3
Completed
- Conditions
- Skin infection
- Registration Number
- ACTRN12617001046392
- Lead Sponsor
- Canterbury District Health Board (Christchurch Hospital campus)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 12
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What is the impact of food on flucloxacillin's Cmax and AUC in healthy volunteers?
How does food affect flucloxacillin's protein binding and beta-lactamase stability?
What are the comparative pharmacokinetics of flucloxacillin with other penicillinase-resistant penicillins when administered with food?
Are there specific biomarkers that correlate with flucloxacillin efficacy in skin infections caused by MRSA or other beta-lactamase-producing pathogens?
What adverse events are associated with flucloxacillin-food interactions and how do they compare to standard-of-care cephalosporins for skin infections?