Role of Cervical Volume and 3 D Power Doppler Indices for Prediction of Preterm Labour
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 300
- 主要终点
- The primary outcome could be the incidence of preterm birth (i.e., births occurring before 37 weeks of gestation) among the study participants.
研究概览
简要总结
The primary aim of this research is to assess the predictive value of 3D cervical volume and 3D power Doppler indices in predicting pregnancies at risk of preterm labor.
Secondary aim: to compare 2D cervical length and 3D cervical length in coronal view for predicting preterm labour.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age : 18-35 years old
- •Singleton pregnancy
- •Gestational age : 18-26 Ws knowing last menstrual period and history of regular mense.
排除标准
- •Multiple gestations (e.g., twins, triplets).
- •History of cervical surgery or cervical cerclage.
- •Known uterine anomalies that could affect cervical assessment.
- •Contraindications for transvaginal ultrasound, such as active vaginal bleeding or infection.
- •Severe fetal anomalies or conditions incompatible with life
结局指标
主要结局
The primary outcome could be the incidence of preterm birth (i.e., births occurring before 37 weeks of gestation) among the study participants.
时间窗: Baseline
Obstetric ultrasound:Trans abdominal and trans vaginal ultrasounds will be performed to all of ladies. During the trans vaginal scan, The Pulsatility Index (PI) of the uterine artery and the cervical length will be measured. All ultrasound exams will be performed by a single investigator utilizing GE (voluson S 8) ultrasonography machines with pulsed and color Doppler capabilities (GE Medical Systems, Zipf, Austria). Cervical length measurements: The distance between the internal and external os will be measured. For the purposes of this study, at least two CL measurements were performed, with the shorter of the two being used in the analysis. Uterine artery Doppler:. The left and right uterine arteries will be measured using trans vaginal ultrasonography with color flow imaging
次要结局
- 1. Gestational Age at Delivery: Measure the gestational age at which participants in the study give birth. This information can help assess whether ultrasonic assessments correlate with the timing of delivery.(Baseline)
- 2. Predictive Parameters: Analyse the individual and combined predictive power of cervical length, vascularity indices, and cervical volume. Determine which of these parameters (or their combinations) show the strongest correlation with preterm birth(Baseline)
研究者
Omar Mohamed Galal
Doctor
Assiut University