Evaluation of the effect of quaternary HPV vaccine in the treatment of women with cervical intraepithelial neoplasia cin1
Phase 3
Recruiting
- Conditions
- Evaluation of the effect of quaternary HPV vaccine in the treatment of women with cervical intraepithelial neoplasia cin1 of Fatemiye Hospitan, Hamadan.
- Registration Number
- IRCT20230522058253N2
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 300
Inclusion Criteria
Age 21 to 45 years
not currently pregnant
not having had more than one sexual partner during their period
received conservative treatment.
women with histologically confirmed CIN 1
Exclusion Criteria
women who became pregnant
received only one dose of the vaccine, or allergic to the vaccine
Those who have been cin 1 for more than 24 month
Those who do not participate in the study (non-cooperation) will be excluded from the study
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Histological biopsy status of CIN 1 lesions in two control and intervention groups. Timepoint: To measure this criterion, women are visited three times (months 12, 18,24) and undergo gynecological examination and pap smear test, colposcopy and annual biopsy and in 18 undergo gynecological examination and pap smear test (in case of pap smear test suspicious) have been placed. Method of measurement: To measure this criterion, women are visited three times (months 12, 18, 24) and undergo gynecological examination and pap smear test, colposcopy and annual biopsy and in 18 undergo gynecological examination and pap smear test (in case of pap smear test suspicious) have been placed.
- Secondary Outcome Measures
Name Time Method