Influencing Factors on Training Efficacy in Healthy Adults

Early Phase 1

Completed

• Conditions: Maximal and Submaximal Parameters of Physical Performance; Health Status
• Interventions: Behavioral: Endurance Training

• Registration Number: NCT02297646
• Lead Sponsor: Universität des Saarlandes

Brief Summary

The purpose of this study is to investigate the effects of carbohydrate intake on training efficacy and health parameters of an endurance training program in healthy adults.

Detailed Description

Carbohydrate availability in endurance exercise seems to attenuate exercise-induced perturbations of cellular homeostasis and consequently diminishes the stimulus for training adaptation. Therefore, a negative relationship with exercise efficacy seems plausible. However, experimental evidence is rare and far from conclusive. Therefore, the present study aims to test the influence of carbohydrate intake on the efficacy of a typical preventive training program.

Study Timeline

• Study Start: 2012-08
• Study First Submitted: 2013-09-10
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Status Verified: 2014-11
• Study First Submitted QC: 2014-11-20
• Last Update Submitted: 2014-11-20
• Study First Posted: 2014-11-21
• Last Update Posted: 2014-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• no diseases
• nonsmoker
• BMI 25-30 kg/m²
• blood pressure <160/100 mm/Hg
• unmedicated
• untrained status
• V̇O2max < 50 mL/kg/min

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Exclusion Criteria

Not provided

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Carbohydrates	Endurance Training	50 grams of carbohydrates 4 times a week for each training session
Control	Endurance Training	no carbohydrate intake

Primary Outcome Measures

Name	Time	Method
Maximum oxygen consumption (VO2max)	24 weeks	VO2max

Secondary Outcome Measures

Name	Time	Method
Resting blood pressure	24 weeks
Ventilatory anaerobic threshold (VT)	24 weeks	VT
Body fat (Skinfold thickness)	24 weeks	Skinfold thickness
Numerous serum parameters from venous blood (LDL, HDL, Cholesterol, Triglycerides)	24 weeks	cardiovascular parameters: * LDL; * HDL; * Cholesterol; * Triglycerides
Resting heart rate	24 weeks

Trial Locations

Locations (1)

Institute of Sports and Preventive Medicine, Saarland University; 🇩🇪 Saarbrücken, Saarland, Germany