Effects of Glucose-fructose Drinks During Training on Lactate Transport and Oxidation and on Endurance Performance
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 17
- 试验地点
- 2
- 主要终点
- Change in lactate transport
研究概览
简要总结
The purpose of this study is to determine whether glucose-fructose intake during training increases lactate transport and oxidation and improve endurance performance.
详细描述
The study will enroll 24 healthy male volunteers. After baseline assessment of lactate transport and endurance performance, subjects will be randomized to either a 3-week intervention arm in which they will train with glucose-fructose intake during training, or to a control arm (water during training). After this 3-week intervention, lactate transport and endurance performance will be assessed again.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •age between 18 and 30 years
- •sedentary
- •BMI between 19 and 25
- •blood pressure lower than 140/90 mmHg
排除标准
- •consumption of more than 10g alcohol per day
- •cardiovascular history
- •electrographic abnormalities at rest
- •consumption of more than one can of soda per day or more than 60g sugars per day
- •any current drug treatment
- •consumption of drugs or illicit substances
- •diabetes mellitus
- •vegetarian
- •food intolerance
- •blood donation or participation to another study <3 months before study inclusion
结局指标
主要结局
Change in lactate transport
时间窗: At baseline (before training) and after the 3-week training protocol
Measurement of lactate production, utilization, oxidation and clearance during a 90 min cycling exercise at 50% VO2 max (measured with 13C-lactate)
次要结局
- Change in muscle monocarboxylate transporters (MCTs) expression and protein content(At baseline (before training) and after the 3-week training protocol)
研究者
Luc Tappy, MD
Professor of Physiology
University of Lausanne