Incidence and Management of Ocular Hypertension Following Deep Anterior Lamellar Keratoplasty

• Conditions: Unrecognized Condition

• Registration Number: NCT04931316
• Lead Sponsor: Mansoura University

Brief Summary

This is a retrospective case series study that included patients who performed deep anterior lamellar keratoplasty and presented with elevated intraocular pressure during follow up.

Detailed Description

This is a retrospective case series study that included patients who performed deep anterior lamellar keratoplasty and presented with elevated intraocular pressure during follow up. Patients' demographic characteristics, medical, and ocular history will be recorded.

Inclusion criteria will include patients who were diagnosed with elevated intraocular pressure (IOP) after DALK surgery performed from 2018 to 2020 with follow up duration more than 6 months. Patients with less than 6 months of follow-up will be excluded from the study.

Patients' demographic characteristics, medical and ocular history will be recorded. Baseline complete ophthalmic examination was performed. It included best corrected visual acuity (BCVA) using Landolt C chart that was converted to log minimum angle of resolution (log MAR) for statistical analysis, slit lamp anterior segment examination (with attention to cornea, bulbar conjunctiva and AC), intraocular pressure measurement using rebound system (I care tonometer, Topcon, Canada), angle assessment and fundus examination using Goldman 3 mirror contact lens.

High IOP was defined as intraocular pressure more than 25 mmHg. Data will be collected with attention to appropriate management done either medical treatment or surgical intervention.

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2021-03-15
• Status Verified: 2021-06
• Study First Submitted: 2021-06-12
• Study First Submitted QC: 2021-06-12
• Study First Posted: 2021-06-18
• Last Update Submitted: 2021-06-18
• Last Update Posted: 2021-06-23
• Primary Completion: 2021-09-20
• Study Completion: 2021-10-20

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• patients who were diagnosed with elevated IOP after DALK surgery performed from 2018 to 2020

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Exclusion Criteria

• Patients with penetrating keratoplasty

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intraocular pressure values	this is a retrospective study . collection of data from patients records over 2 months	assessment of intraocular pressure after lamellar keratoplasty

Trial Locations

Locations (1)

Mansoura university; 🇪🇬 Mansoura, Dakahlyia, Egypt