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临床试验/NCT04931316
NCT04931316Unknown不适用

Incidence and Management of Ocular Hypertension Following Deep Anterior Lamellar Keratoplasty

Mansoura University1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2021年3月15日最近更新:
适应症

试验速览

阶段
不适用
入组人数
10
试验地点
1
主要终点
Intraocular pressure values

研究概览

简要总结

This is a retrospective case series study that included patients who performed deep anterior lamellar keratoplasty and presented with elevated intraocular pressure during follow up.

详细描述

This is a retrospective case series study that included patients who performed deep anterior lamellar keratoplasty and presented with elevated intraocular pressure during follow up. Patients' demographic characteristics, medical, and ocular history will be recorded.

Inclusion criteria will include patients who were diagnosed with elevated intraocular pressure (IOP) after DALK surgery performed from 2018 to 2020 with follow up duration more than 6 months. Patients with less than 6 months of follow-up will be excluded from the study.

Patients' demographic characteristics, medical and ocular history will be recorded. Baseline complete ophthalmic examination was performed. It included best corrected visual acuity (BCVA) using Landolt C chart that was converted to log minimum angle of resolution (log MAR) for statistical analysis, slit lamp anterior segment examination (with attention to cornea, bulbar conjunctiva and AC), intraocular pressure measurement using rebound system (I care tonometer, Topcon, Canada), angle assessment and fundus examination using Goldman 3 mirror contact lens.

High IOP was defined as intraocular pressure more than 25 mmHg. Data will be collected with attention to appropriate management done either medical treatment or surgical intervention.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • patients who were diagnosed with elevated IOP after DALK surgery performed from 2018 to 2020

排除标准

  • Patients with penetrating keratoplasty

结局指标

主要结局

Intraocular pressure values

时间窗: this is a retrospective study . collection of data from patients records over 2 months

assessment of intraocular pressure after lamellar keratoplasty

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Amgad Mahmoud El Nokrashy

Lecturer of Ophthalmology

Mansoura University

研究点 (1)

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