"Efficacy of Intermittent Enteral Nutrition Versus Continuous Administration in Intensive Care Patients for the Reduction of Complications. Randomized Clinical Trial"
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Enteral Nutrition
- Sponsor
- Complejo Hospitalario Universitario de Albacete
- Enrollment
- 190
- Locations
- 1
- Primary Endpoint
- Respiratory Complications
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The goal of this clinical trial is to Determine efficacy of intermittent enteral nutrition vs continuous enteral nutrition in adults patients with a nasogastric tube in a intensive care unit.
The main question[s] it aims to answer are:
- Reduction of gastrointestinal and respiratory complications
- Evaluate the achievement of the caloric objective Informed consent will be requested from participants who meet the inclusion criteria.
The participants will be randomized into two groups: control group (continuous enteral nutrition) or experimental group (intermittent enteral nutrition) Researchers will compare intermittent enteral nutrition vs continuous to see if there is a reduction in gastrointestinal and respiratory complications.
Investigators
Maria Dolores Saiz Vinuesa
Principal Investigator
Complejo Hospitalario Universitario de Albacete
Eligibility Criteria
Inclusion Criteria
- •Patients admitted to ICU of University General Hospital of Albacete
- •Need for enteral nutrition by nasogastric tube in the first 48 hours
- •Signed informed consent
Exclusion Criteria
- •Insulin dependent diabetic patients
- •Abdominal surgery
- •Dire prognosis
Outcomes
Primary Outcomes
Respiratory Complications
Time Frame: during ICU stay (maximum 15 days)
Respiratory aspiration of gastric content
Gastrointestinal Complications
Time Frame: during ICU stay (maximum 15 days)
Digestive intolerance: Diarrhea, vomiting, increased gastric residual volume(GRV)
Secondary Outcomes
- ICU Stay(From date of randomization until 100 months)
- Achievement of the caloric objective(during ICU stay (up to 15 days))
- Nutritional status: Biochemical values(up to two days after admission to the ICU)
- Nutritional status: MNA(up to two days after admission to the ICU)
- Changes in blood glucose(during ICU stay (maximum 15 days))
- Mortality(until the date of death from any cause until 100 months)
- Change of type of EN administration(during ICU stay (maximum 15 days))
- Nutritional status:Glim Criteria(up to two days after admission to the ICU)