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A Study Of GW685698X For The Treatment Of Perennial Allergic Rhinitis In Pediatrics

Phase 3
Completed
Conditions
Rhinitis, Allergic, Perennial
Interventions
Drug: GW685698X aqueous nasal spray
Registration Number
NCT00116883
Lead Sponsor
GlaxoSmithKline
Brief Summary

The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound GW685698X compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in children 2 to 11 years of age with perennial allergic rhinitis.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
90
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm 1GW685698X aqueous nasal spray-
Primary Outcome Measures
NameTimeMethod
HPA axis function at baseline and after 6 weeks of treatment as measured by 24 hour urine and serial serum cortisol assessments in domiciled subjects
Secondary Outcome Measures
NameTimeMethod
Results of adverse event, laboratory, nasal examination, vital sign, ECG and pharmacokinetic assessments.

Trial Locations

Locations (1)

GSK Investigational Site

🇺🇸

Richmond, Virginia, United States

GSK Investigational Site
🇺🇸Richmond, Virginia, United States

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