IRCT20150902023864N3RecruitingPhase 3
Comparison of the therapeutic effect of 5% ibuprofen nanoemulsion gel and commercial ibuprofen gel on knee osteoarthritis pain
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Recruiting
- Enrollment
- 124
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 80 years (—)
- Sex
- All
Inclusion Criteria
- •Unilateral or bilateral knee osteoarthritis with radiographic evidence according to American College of Rheumatology criteria and the International Osteoarthritis Research Society which is diagnosed through physical examination by the physician
- •Having mild to moderate knee osteoarthritis pain
- •Written informed consent to participate in the study
Exclusion Criteria
- •Very severe knee pain
- •Recent lower limb injury or surgery such as repair and joint replacement
- •Inflammatory arthritis
- •Metabolic bone disease
- •Fracture and/or dislocation of knee
- •History of an open wound in the affected knee
- •History of adverse reactions to NSAIDs
- •Diabetes and Lupus disease
- •Corticosteroid injection into the knee within 30 days of intervention
- •Multiple sclerosis (MS)
- •The dermatologic disorder which affected the surrounding skin of the knees
- •Uncontrolled heart failure
- •High blood pressure
- •Chronic renal failure
- •Respiratory diseases
- •History of alcohol or drug abuse
- •History of neurological disorders affecting sensory, motor or cognitive function
Investigators
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