Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- VAS of brachial plexus innervated area
研究概览
简要总结
The retrograde infraclavicular brachial plexus block has been proved an effective and safe approach. Realtime ultrasound guide will facilitate a successful peripheral nerve block. The purpose of this study was to determine the medium effective volume required to produce an effective retrograde infraclavicular block using an ultrasound (US)-guided technique.
详细描述
Thirty adults undergoing elective upper limb surgery received an US-guided retrograde infraclavicular block. The initial concentration of 0.5% ropivacaine injected was 30 ml, which was subsequently varied at a ratio of 1: 1.2 for each consecutive patient according to the response of the previous patient. The medium effective volume (EV50) was determined using the Dixon and Massey up-and-down method. The effective volume in 95% of patients (EV95) was calculated using probit regression.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elected upper extremity operations
- •BMI 17~30kg/m2
排除标准
- •Infection at injection site
- •Coagulation Dysfunction
- •Phrenic nerve palsy
- •Pneumothorax
- •Recurrent laryngeal nerve palsy
- •Clavicle fracture combined with nerve damage
结局指标
主要结局
VAS of brachial plexus innervated area
时间窗: 20 minutes
effect and side effects of the present block approach for brachial plexus.
次要结局
- medium effective ropivacaine volume(about 2 months)