Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Upper Extremity Injury Trauma
- Sponsor
- Beijing Jishuitan Hospital
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- VAS of brachial plexus innervated area
- Status
- Completed
- Last Updated
- 15 years ago
Overview
Brief Summary
The retrograde infraclavicular brachial plexus block has been proved an effective and safe approach. Realtime ultrasound guide will facilitate a successful peripheral nerve block. The purpose of this study was to determine the medium effective volume required to produce an effective retrograde infraclavicular block using an ultrasound (US)-guided technique.
Detailed Description
Thirty adults undergoing elective upper limb surgery received an US-guided retrograde infraclavicular block. The initial concentration of 0.5% ropivacaine injected was 30 ml, which was subsequently varied at a ratio of 1: 1.2 for each consecutive patient according to the response of the previous patient. The medium effective volume (EV50) was determined using the Dixon and Massey up-and-down method. The effective volume in 95% of patients (EV95) was calculated using probit regression.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Elected upper extremity operations
- •BMI 17\~30kg/m2
Exclusion Criteria
- •Infection at injection site
- •Coagulation Dysfunction
- •Phrenic nerve palsy
- •Pneumothorax
- •Recurrent laryngeal nerve palsy
- •Clavicle fracture combined with nerve damage
Outcomes
Primary Outcomes
VAS of brachial plexus innervated area
Time Frame: 20 minutes
effect and side effects of the present block approach for brachial plexus.
Secondary Outcomes
- medium effective ropivacaine volume(about 2 months)