Glaucoma After Congenital Cataract Surgery
- Conditions
- Congenital CataractGlaucoma
- Registration Number
- NCT04342052
- Lead Sponsor
- Sun Yat-sen University
- Brief Summary
To determine the incidence of glaucoma following bilateral congenital cataract removal and estimate the associated risk factors in a large cohort to provide guidance for clinical practice.
- Detailed Description
A prospective longitudinal cohort study of pediatric patients who underwent surgery for congenital/infantile cataracts between January 2011 and December 2025 was performed.
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 351
Inclusion Criteria
- a diagnosis of bilateral congenital cataracts, the etiologies include congenital idiopathic cataract and congenital cataract associated with a systemic syndrome or ocular anomalies;
- cataract surgery performed in ZOC;
- age at cataract removal younger than 16 years;
Exclusion Criteria
- the preoperative IOP was above 21 mm Hg;
- family history of glaucoma;
- signs of preoperative glaucoma were present, such as corneal clouding, corneal enlargement, excessive cup-disc ratio and myopic shift;
- ocular trauma history;
- previous surgery intervention and
- they were noncompliant with our follow-up protocol to monitor the occurrence of glaucoma and glaucoma suspect.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the incidence of glaucoma after congenital cataract surgery baseline A Kaplan-Meier analysis was used
- Secondary Outcome Measures
Name Time Method Risk factors of glaucoma after congenital cataract surgery baseline Piecewise exponential survival models with mixed effects (PEWSMME) were used.(variables including demographic characters, surgery categories, clinical history, length of follow up).
Trial Locations
- Locations (1)
Zhongshan Ophthalmic Center, Sun Yat-sen Univerisity
🇨🇳Guangzhou, Guangdong, China