Suspected Glaucoma and Glaucoma After Congenital and Infantile Cataract Surgery: A Longitudinal Study in China
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 241
- 试验地点
- 1
- 主要终点
- the incidence of suspected glaucoma/glaucoma after congenital cataracts
研究概览
简要总结
Pediatric patients who have undergone surgery for congenital or infantile cataracts have a risk of developing suspected glaucoma and glaucoma, but the current evidence does not address our understanding of the incidence and associated risk factors of suspected glaucoma/glaucoma for application in clinical standard care. Therefore, this study investigated the incidence of and risk factors for suspected glaucoma/glaucoma in patients who have undergone surgery for congenital/infantile cataracts.
详细描述
A prospective longitudinal cohort study of pediatric patients who underwent surgery for congenital/infantile cataracts between January 2011 and December 2021 was performed.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 10 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a diagnosis of congenital/infantile cataracts without any surgical intervention;
- •age younger than 10 years;
- •cataract surgery performed at the Zhongshan Ophthalmic Center after enrollment
排除标准
- •a preoperative IOP above 21 mm Hg;
- •the presence of any preoperative sign of glaucoma, such as corneal enlargement, corneal clouding, excessive optic nerve cupping, or a family history of glaucoma;
- •the presence of ocular trauma or other abnormalities, such as microcornea, microphthalmia, persistent hyperplastic primary vitreous, Peters anomaly, congenital aniridia, Marfan syndrome, lens dislocation, retinitis pigmentosa, high myopia, fundus lesions, rubella, and Lowe syndrome.
结局指标
主要结局
the incidence of suspected glaucoma/glaucoma after congenital cataracts
时间窗: 3 years
A Kaplan-Meier analysis was used.
Risk Factors of suspected glaucoma/glaucoma after congenital cataracts
时间窗: 3 years
Cox regression analysis was assessed
次要结局
未报告次要终点
研究者
Haotian Lin
Principal Investigator
Sun Yat-sen University