The association of bradycardia and cholinesterase inhibitor use among older adults living with dementia: A retrospective cohort study in a university hospital
Completed
- Conditions
- Dementia BradycardiaDementiaCholinesterase inhibitorBradycardia
- Registration Number
- TCTR20210427005
- Lead Sponsor
- Geriatric medicine, medicine department, Ramathibodi hospital, Mahidol university
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 1044
Inclusion Criteria
1. Newly diagnosed dementia patients (Dementia in Alzheimer's disease, Vascular dementia, Dementia in other diseases classified elsewhere, Unspecified dementia)
at OPD memory and OPD geriatric, Ramathibodi hospital between 01/01/2009 and 31/12/2019
2. Age at least 60 years or more
3. Existed at least 2 heart rate record from index date
Exclusion Criteria
1. Pre-existing bradycardia ( second degree AV block Mobitz type II, third degree AV block, pacemaker implanted) patients
2. No index date of dementia diagnosis or referral patients from others hospital
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Repeated bradycardia until bradycardia was existed or death or loss follow up Heart rate less than 60 beat per minute 2 times
- Secondary Outcome Measures
Name Time Method association factors of bradycardia in dementia patients until bradycardia was existed or death or loss follow up Heart rate less than 60 beat per minute 2 times