Acetyl- and butyrylcholinesterase-activity in patients with schizophrenic disorders
- Conditions
- F20Schizophrenia
- Registration Number
- DRKS00023143
- Lead Sponsor
- Klinik für Psychiatrie und Psychotherapie III Universitätsklinikum Ulm
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 73
Inclusion Criteria
Age > 18 years
DSM-classified schizophrenic disease (pre-existing or initial diagnosis)
verbal and written consent of the patients before starting the measurements
Exclusion Criteria
Age < 18 years
Cognitive impairment that makes participation in the study impossible
Severe visual and hearing impairments
patients who are not able to give informed consent
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method AChE-activity in patients with schizophrenia compared to the healthy collective<br>BChE-activity in patients with schizophrenia compared to the healthy collective
- Secondary Outcome Measures
Name Time Method Correlation of BNNS (Brief Negative Symptom Scale) with AChE-, BChE-activity<br>Correlation of SNS (self-evaluation of negative symptoms) with AChE-, BChE-activity<br>Correlation between the course of AChE-, BChE- activity and the need for antipsychotics (total dose, dose per 24 hours)<br>Correlation between disease duration, based on initial diagnosis and AChE-, BChE-activity.