Evaluation of the effect of green tea extracts in osteoarthritis
- Conditions
- Osteoarthritis.Primary gonarthrosis, bilateral
- Registration Number
- IRCT201307188300N2
- Lead Sponsor
- Shiraz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
patients of both sexes with mild to moderate osteoarthritis of the knee, in the age group 40 to 75 years, referred to the Physical Medicine and Rehabilitation, Shiraz, Iran.
Exclusion criteria: patients with severe osteoarthritis; patients suffering ischemic heart disease or heart failure; patients with renal function impairment; patients with hepatic failure; pregnant women; breastfeeding women; women who stop contraception techniques to become pregnant; patients who had a history of sensitivity to caffeine; patients whose diets are effective for weight loss or gain, and planned to decrease or increase their weight; patients who have recently begun the exercise to protect joints or changing their activity levels; patients treated with alkaline agents, for any reason, who was not able to discontinue their medications; patients treated with warfarin for any reason, that the patient was unable to stop his warfarin; patients with a history of gastrointestinal bleeding with non-steroidal anti-inflammatory drugs; patients who for any reason were not able to express their pain (eg patients with mental retardation or patients with Alzheimer's); patients who did not receive the necessary support for their drugs or they are not likely to be followed (eg, patients who were residents of older people centers ); patients who do not continure the trial: intolerable side effects for the patient (Gastrointestinal side effects such as increased gastric acid secretion, diarrhea or constipation, headache, palpitations, insomnia, irritability, restlessness);discontinuation of drugs consumption for any reason and not to follow treatment for any reason.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Function. Timepoint: at the beginning and 1 month after intervention. Method of measurement: WOMAC quastionaire.;Pain. Timepoint: at the beginning and 1 month after intervention. Method of measurement: WOMAC quastionaire.;Joint stiffness. Timepoint: at the beginning and 1 month after intervention. Method of measurement: WOMAC quastionaire.
- Secondary Outcome Measures
Name Time Method