Comparison of surgical site infections with or without subcutaneous amikacin in patients of emergency laparotomy- A Randomised Controlled Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Proportion of patients in whom surgical site infection as defined by grade 2 CDC criteria
研究概览
简要总结
A combination of antimicrobial therapy improved surgical technique and intensive care support may improve the outcome of such cases In cases of perforation peritonitis abdominal closure is sometimes challenging to the surgeon where bowel become oedematous in severe peritonitis. There will be outpouring of fluid or pus from peritoneal cavity to the surgical wound subcutaneous tissues that can lead to wound infection and wound dehiscence. If the wound kept open then there is high risk for developing nosocomial infection. Incisional surgical site infection causes increasing patient suffering and a decreased quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 15.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •All patients presenting to surgery emergency who are undergoing exploratory laparotomy.
排除标准
- •Hyperbilirubinemia Not able to close abdomen Acute kidney disease Chronic kidney disease Immunocompromised state.
结局指标
主要结局
Proportion of patients in whom surgical site infection as defined by grade 2 CDC criteria
时间窗: 2nd day, 4th day, 7th day , 1 month
次要结局
- 1. Proportion of wound dehiscence(2. Duration of hospital stay in days)
研究者
Dr Rahul Kumar
Maulana Azad Medical College