Effectiveness of Ointment Containing Hops Nanoparticles for Relieving Early Menopausal Symptoms
Phase 3
- Conditions
- Menopause.Menopausal and female climacteric states , Other specified menopausal and perimenopausal disordersN95.1 ,N95
- Registration Number
- IRCT2016062526405N1
- Lead Sponsor
- Vice-Chancellor in Research Affairs Research Institute for Endocrine Sciences, Shahid Beheshti Unive
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
•last menstrual period between 12 months and 2 years before the beginning of the study ;
•age between 45 and 60 years;
•not using of any hormone replacement therapies in the past 6 months;
•Not having any allergic disorders to phytoestrogens;
•not having abnormal uterine bleeding, breast cancer and uterine cancer;
•not having a past history of breast cancer, endometrial cancer,
thromboembolism disorders and coronary heart disease;
•not having any chronic dermatologic disorders.
Exclusion criteria:
Patients presenting with systematic illness, allergic reactions ,and use of any interfering drugs were excluded.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Early Menopausal Symptoms. Timepoint: before-after. Method of measurement: Menopausal Rating Scale.
- Secondary Outcome Measures
Name Time Method Stradiol level. Timepoint: before-after. Method of measurement: biochemical tests.;Cytokine profile. Timepoint: before-after. Method of measurement: inflammatory index analysis.