A comparison of the analgesic efficacy of oral and intravenous paracetamol (perfalgan) in a day case setting - Oral versus IV paracetamol

• Conditions: We will perform a double blind randomised comparison of oral paracetamol versus intravenous paracetamol (Perfalgan) in patients undergoing knee arthroscopy in a day surgery setting.

• Registration Number: EUCTR2006-002208-32-GB
• Lead Sponsor: York Hospital NHS Trust

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-09-18
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

All patients on the list for day case knee arthroscopy aged between 18 to 60 years and weighing between 50 to 90 kg will be eligible for the study.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

Age <18 and >60 years, ASA 3 or 4 (American society of anaestesiologist classification - ASA 3 & 4 are sicker patients than ASA 1 & 2), known allergy to paracetamol, patients who had paracetamol in the last 12 hours, pregnant or breast feeding women, history of complete non-responsiveness to acetaminophen, inflammatory bowel disease, chronic pain patients, arthroscopies related to infection (where surgeon would not instil local anaesthetic), bilateral arthroscopies.

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified