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Acute Effects of High-intensity Interval Training With Mindfulness-based Recovery on Executive Function in Children

Not Applicable
Recruiting
Conditions
Healthy Volunteers
Interventions
Behavioral: MF-only
Behavioral: Sitting rest
Behavioral: MF-HIIT
Behavioral: HIIT-only
Registration Number
NCT06270589
Lead Sponsor
Purdue University
Brief Summary

The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive function (EF) in 10-12 years old children. The main question it aims to answer are:

Question 1: Whether a single bout of 20-min MF-HIIT has larger beneficial effect on EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Question 2: Whether a single bout of 20-min MF-HIIT has a larger beneficial effect on brain functioning, as measured by the N2 and P3 components of event-related potential (ER) during EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Participants will visit the laboratory on 5 separate days (\> 2-day washout between days) in which they have not previously participated in structured physical activities.

Participants will complete the testing and/or receive treatments below:

Day 1:

* Kaufman Brief Intelligence Test (KBIT) to assess intelligence quotient

* Treadmill-based exercise test to measure cardiorespiratory fitness (maximum oxygen consumption)

Days 2-5

* Each day, participants will complete each of the four intervention conditions (MF-HIIT, MF-only, HIIT-only, sitting)

* Participants' heart rate and self-reported affect and rating of physical exertion will be measured

* Participants will complete a modified flanker task and a task-switching task to assess inhibitory control and cognitive flexibility

* Participants will wear an EEG cap to measure the N2 and P3 components of the event-related potential during the inhibitory control and cognitive flexibility performance

Researcher will compare the cognitive outcome measures following the MF-HIIT, MF-only, and HIIT-only conditions with the sitting condition to see if MF and HIIT has beneficial effects on children's EF.

Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
60
Inclusion Criteria
  • Age between 10-12 years old
  • Intelligence Quotient ≥ 85
  • Capable of performing exercise based on pre-participation health screening
  • No formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)
Exclusion Criteria
  • Age outside of the range of 10-12 years old
  • Intelligence Quotient < 85
  • No capable of performing exercise based on pre-participation health screening
  • Has formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)

Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
A Single Bout Of MindfulnessMF-only-
A Single Bout Of Sitting RestSitting rest-
A Single Bout Of Mindful High-Intensity Interval Training (Mindful HIIT)MF-HIIT-
A Single Bout Of High-Intensity Interval Training (HIIT)HIIT-only-
Primary Outcome Measures
NameTimeMethod
Inhibition speedAt the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Inhibition speed will be assessed by the response time (ms) during a child-friendly flanker task.

N2-ERPAt the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The N2 component of event-related brain potentials is a neuroelectric index of conflict processing. Increased amplitude of N2 reflects increased neural activation to detect and resolve conflicts.

P3-ERPAt the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The P3 component of event-related brain potentials is a neuroelectric index of attention. Increased amplitude of P3 reflects greater allocation of attentional resources and the decreased latency of P3 reflects the faster information processing speed.

Inhibition accuracyAt the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Inhibition accuracy will be assessed by the response accuracy (%) during a child-friendly flanker task.

Shifting speedAt the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The shifting speed will be assessed by the response time (ms) during a child-friendly switching task.

Shifting accuracyAt the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The shifting accuracy will be assessed by the response accuracy (%) during a child-friendly switching task.

Secondary Outcome Measures
NameTimeMethod
Heart RateHeart rate will be measured at every minute (minutes 0, 1, 2, 3, 4, ...., 18, 19, 20) during the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Heart rate will serve as a manipulation check on the intensity of prescribed exercise.

State Mindfulness Scale for Physical Activity (SMSPA)Immediately after completing the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

A developmentally-appropriate and validated 12-item, 5-point Likert scaled (0-4), instrument to measure self-reported mindfulness state in children aged above 10 years old. This measure will serve as a manipulation check on mindfulness induction during each of the 4 intervention conditions.

Rating of perceived exertionMeasure at 0 second, 90 seconds, 180 seconds, 270 seconds, 360 seconds, 450 seconds, 540 seconds, 630 seconds, 720 seconds, 810 seconds, 900 seconds, 990 seconds, 1080 seconds and 1200 seconds of the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The 10-point Children's OMNI rating of perceived exertion will be used as a manipulation check on the intensity of prescribed exercise for the school-based programs as well as the laboratory-based acute interventions.

Trial Locations

Locations (1)

Lambert, 800 West Stadium Avenue

🇺🇸

West Lafayette, Indiana, United States

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