Skip to main content
Clinical Trials/NCT06270589
NCT06270589
Recruiting
Not Applicable

Supporting High-intensity Interval Training With Mindfulness for Enhancing Childhood Executive Function

Purdue University1 site in 1 country60 target enrollmentJune 15, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy Volunteers
Sponsor
Purdue University
Enrollment
60
Locations
1
Primary Endpoint
Inhibition speed
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The goal of this randomized cross-over trial is to learn about the effect of a single bout of 20-min mindfulness-based high-intensity interval training (MF-HIIT), MF-only, and HIIT-only in relative to sitting rest on executive function (EF) in 10-12 years old children. The main question it aims to answer are:

Question 1: Whether a single bout of 20-min MF-HIIT has larger beneficial effect on EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Question 2: Whether a single bout of 20-min MF-HIIT has a larger beneficial effect on brain functioning, as measured by the N2 and P3 components of event-related potential (ER) during EF performance than that following a 20-min session of MF-only and HIIT-only in relative to the sitting rest

Participants will visit the laboratory on 5 separate days (> 2-day washout between days) in which they have not previously participated in structured physical activities.

Participants will complete the testing and/or receive treatments below:

Day 1:

  • Kaufman Brief Intelligence Test (KBIT) to assess intelligence quotient
  • Treadmill-based exercise test to measure cardiorespiratory fitness (maximum oxygen consumption)

Days 2-5

  • Each day, participants will complete each of the four intervention conditions (MF-HIIT, MF-only, HIIT-only, sitting)
  • Participants' heart rate and self-reported affect and rating of physical exertion will be measured
  • Participants will complete a modified flanker task and a task-switching task to assess inhibitory control and cognitive flexibility
  • Participants will wear an EEG cap to measure the N2 and P3 components of the event-related potential during the inhibitory control and cognitive flexibility performance

Researcher will compare the cognitive outcome measures following the MF-HIIT, MF-only, and HIIT-only conditions with the sitting condition to see if MF and HIIT has beneficial effects on children's EF.

Further, researcher will compare the cognitive outcome measures following the MF-HIIT compared with MF-only and HIIT-only conditions to see if combining MF with HIIT has greater beneficial effects on children's EF than MF and HIIT alone.

Registry
clinicaltrials.gov
Start Date
June 15, 2024
End Date
May 31, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Shih-Chun Kao

Assistant Professor

Purdue University

Eligibility Criteria

Inclusion Criteria

  • Age between 10-12 years old
  • Intelligence Quotient ≥ 85
  • Capable of performing exercise based on pre-participation health screening
  • No formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)

Exclusion Criteria

  • Age outside of the range of 10-12 years old
  • Intelligence Quotient \< 85
  • No capable of performing exercise based on pre-participation health screening
  • Has formal diagnosis of cognitive disorders (e.g., attention deficit hyperactivity disorder) and neurological diseases (e.g., epilepsy)

Outcomes

Primary Outcomes

Inhibition speed

Time Frame: At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Inhibition speed will be assessed by the response time (ms) during a child-friendly flanker task.

N2-ERP

Time Frame: At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The N2 component of event-related brain potentials is a neuroelectric index of conflict processing. Increased amplitude of N2 reflects increased neural activation to detect and resolve conflicts.

P3-ERP

Time Frame: At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The P3 component of event-related brain potentials is a neuroelectric index of attention. Increased amplitude of P3 reflects greater allocation of attentional resources and the decreased latency of P3 reflects the faster information processing speed.

Inhibition accuracy

Time Frame: At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

Inhibition accuracy will be assessed by the response accuracy (%) during a child-friendly flanker task.

Shifting speed

Time Frame: At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The shifting speed will be assessed by the response time (ms) during a child-friendly switching task.

Shifting accuracy

Time Frame: At the baseline before and about 10-min after the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.

The shifting accuracy will be assessed by the response accuracy (%) during a child-friendly switching task.

Secondary Outcomes

  • Heart Rate(Heart rate will be measured at every minute (minutes 0, 1, 2, 3, 4, ...., 18, 19, 20) during the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.)
  • State Mindfulness Scale for Physical Activity (SMSPA)(Immediately after completing the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.)
  • Rating of perceived exertion(Measure at 0 second, 90 seconds, 180 seconds, 270 seconds, 360 seconds, 450 seconds, 540 seconds, 630 seconds, 720 seconds, 810 seconds, 900 seconds, 990 seconds, 1080 seconds and 1200 seconds of the 20-min intervention on Day 2, Day 3, Day 4, and Day 5.)

Study Sites (1)

Loading locations...

Similar Trials