Video-assisted thoracic surgery versus open lobectomy for lung cancer: a randomized prospective trial

Phase 4

Recruiting

• Conditions: lung cancer; pulmonary carcinoma; 10029107

• Registration Number: NL-OMON37381
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 160

Inclusion Criteria

Patients selected by multidisciplinary oncologic team to undergo lobectomy
Non-small cell lung carcinoma, pathologically confirmed or strong suspicion based on imaging.
T1 or T2a (<= 5 cm) on computer tomography (CT).
Primary aim is lobectomy.
Tumor is not in close relation to central structures (main bronchus, pulmonary artery or pulmonary veins) and is surrounded by lung parenchym (based on CT).
Clinically staged N0 or N1 (lymfnodes), M0 (no distant metastasis) after clinical staging according to the current Dutch guideline (may 2011).

Exclusion Criteria

T2b, T3 or T4 tumor (7th guideline TNM classification NSCLC).
Mediastinal lymph node metastasis (N2, N3).
Distant metastasis (M1).
Previous thoracic surgery on same side.
Pneumonectomy as primary aim.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary endpoints are postoperative quality of life, number of dissected<br /><br>mediastinal lymph nodes for oncologic staging, hospital length of stay and<br /><br>overall costs. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary endpoints include procedural complication rates, pulmonary function<br /><br>and survival.</p><br>