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Clinical Trials/NCT06332768
NCT06332768
Completed
N/A

Comparison of High Flow Oxygenation, Noninvasive Ventilation and Standard Oxygen Therapy in the Early Post-extubation Period in Patients With Acute Respiratory Distress Syndrome

Northern State Medical University1 site in 1 country60 target enrollmentSeptember 1, 2017
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ConditionsMechanical Ventilation ComplicationWeaning FailureAcute Respiratory Distress SyndromeHigh-flow Oxygenation

Overview

Phase
N/A
Intervention
Not specified
Conditions
Mechanical Ventilation Complication
Sponsor
Northern State Medical University
Enrollment
60
Locations
1
Primary Endpoint
Weaning failure
Status
Completed
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The weaning failure is a paramount challenge when aggressive discontinuation of respiratory support in ARDS. The aim of the study is to improve weaning safety and efficacy by a transient postextubation non-invasive respiratory support.

Detailed Description

HFNO (high-flow nasal oxygenation and NIV (non invasive ventilation) are to be randomly compared in the ARDS postextubation period.

Registry
clinicaltrials.gov
Start Date
September 1, 2017
End Date
March 1, 2022
Last Updated
2 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Northern State Medical University
Responsible Party
Principal Investigator
Principal Investigator

Mikhail Y. Kirov

Head of the anesthesiology and intensive care department

Northern State Medical University

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • •Severe ICU-aquired weakness Severe COPD

Outcomes

Primary Outcomes

Weaning failure

Time Frame: 48 hrs

Weaning failure and re-intubation or recanulation

Study Sites (1)

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