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Clinical Trials/NCT02396589
NCT02396589
Completed
Not Applicable

Feasibility of a Novel Intervention to Improve Participation After Stroke

Washington University School of Medicine1 site in 1 country15 target enrollmentJanuary 19, 2015
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Washington University School of Medicine
Enrollment
15
Locations
1
Primary Endpoint
Rate and Severity of Falls (Calculated With an Algorithm)
Status
Completed
Last Updated
8 months ago

Overview

Brief Summary

Stroke is one of the most serious, disabling health conditions in the United States. Patients who undergo rehabilitation treatment for stroke have a high rate of disability. Poor outcomes for many persons with stroke may be low because of incomplete treatment. The investigators will conduct a randomized controlled trial and a process evaluation to examine the feasibility, safety, and preliminary efficacy of an enhanced rehabilitation transition program, Community Participation Transition after Stroke (COMPASS), designed to bridge inpatient rehabilitation and the home to support the performance of everyday activities.

Detailed Description

We propose an enhanced rehabilitation transition program: Community Participation Transition after Stroke (COMPASS) is a compensatory intervention consisting of one pre-discharge and five post-discharge home visits by an occupational therapist to supplement usual care. This intervention is focused on resolving barriers to independence in daily activities and participation using environmental support and active practice of daily activities in an individual's real home (versus an idealized clinical setting). This is a new combination of evidence-based compensatory treatments delivered in a novel treatment setting (transition to home). Our long-term goal is the development of an effective intervention for a transition home designed to prevent excess disability for people living with stroke that could have an immediate effect and high public health significance.16 We will recruit 40 patients currently undergoing inpatient rehabilitation (IR) for ischemic stroke from longitudinal studies of stroke at Washington University School of Medicine (WUSM) and randomize them to receive six additional sessions of the enhanced rehabilitation transition program or attention control. Exploratory participation outcomes will be assessed by blinded evaluators at baseline, 6 months, 9 months, and 12 months after stroke. We will test the central hypothesis that COMPASS will be acceptable, feasible, and superior to attention control on measures of participation and daily activity performance at 6 months after stroke.

Registry
clinicaltrials.gov
Start Date
January 19, 2015
End Date
December 13, 2016
Last Updated
8 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Susan Stark

Assisstant Professor of Neurology and Occupational Therapy

Washington University School of Medicine

Eligibility Criteria

Inclusion Criteria

  • ≥45 years old
  • acute ischemic stroke, verified by a neurologist
  • baseline National Institutes of Health Stroke Scale (NIHSS) ≥8
  • independent in activities of daily living prior to stroke (premorbid Rankin score of ≤2)
  • plan to discharge to home

Exclusion Criteria

  • severe terminal systemic disease that limits life expectancy to \<6 months
  • previous disorder (e.g., dementia) that makes interpretation of the self-rated scales difficult or a Short Blessed Test (SBT) score of ≥9 (indicating significant cognitive impairment)
  • moderate to severe aphasia, as determined by the NIHSS Best Language rating of ≥2
  • residence in a congregate living facility
  • not eligible for a therapeutic pass

Outcomes

Primary Outcomes

Rate and Severity of Falls (Calculated With an Algorithm)

Time Frame: 12 months

We will explore the safety of the intervention by determining the rate and severity of falls (calculated with an algorithm). Scores are as follows: 0, those with no falls, 1, those with one fall without serious injury, 2, those with at least two falls without serious injury, and 3, those with one or more falls causing serious injury. Maximum score of three indicates an increased severity of fall. We will compare the difference in scores between groups using t-tests.

Secondary Outcomes

  • Intervention Dose, Number of Treatment Sessions(2 months)
  • Health Care Utilization, Number of Emergency Department Visits(12 months)
  • Intervention Dose (Minutes)(2 months)
  • Health Care Utilization, Days of Hospitalization(12 months)

Study Sites (1)

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